The secret to beautiful bare skin?
Our gold standard picosecond laser*

Smooth, pigment free skin | Fast, safe & effective

*The gold standard picosecond laser with the largest body of clinical evidence

Give patients beautiful bare skin

The World’s 1st 755nm Picosecond Laser

The PicoSure Pro device delivers 755nm energy in picoseconds; the delivery is so quick that it spares the skin from high thermal damage while optimally targeting unwanted pigment, wrinkles, acne scars and pores with less downtime than traditional lasers.

  • 1 Zoom handpiece (2-6mm) and 4 fixed handpieces (5, 6, 8, 10mm) with adjustable fluence for customizable treatments
  • Platinum focus™ lens for unique skin revitalization with no downtime
  • Flat lens for treating unwanted pigment in all skin types
  • Optional 532nm and 1064nm add on for tattoo removal capabilities

The Power to Transform

With over 1 million treatments performed and 100% patient satisfaction1, PicoSure Pro has become a popular and trusted treatment worldwide.

Key Indications

  • Remove unwanted pigment safely and effectively in all skin types; the first picosecond device FDA-cleared to treat melasma pigment, nevus of Ota and Hori’s nevus
  • Reduce wrinkles, fine lines, acne scars and pore size with no downtime
  • Improve overall skin tone & texture; providing patients with lighter, brighter and more radiant complexion
  • PicoSure combines patented PressureWave™ Technology with the use of three nominal wavelengths (532, 755 and 1064nm) alongside stringent certifications from the FDA and TGA to give you the confidence and ability to treat even the most complex tattoo indications.
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PicoSure Pro device

Revolutionalising the industry in Picoseconds

Picosure Pro Before and Afters

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Before and After 1 Pigment Treatment

Courtesy of Lethbridge Plastic Surgery

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Before and After 1 Pigment Treatmentery

Courtesy of Lethbridge Plastic Surgery

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Before and After 1 Pigment Treatment

Courtesy of Lethbridge Plastic Surgery

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Before and After 2 Pigment Treatments

Courtesy of Lethbridge Plastic Surgery


See it in action


Should I use a topical anesthetic while providing this treatment?

Topical anesthetic may be administered to increase patient comfort; although this is not routinely needed.

How long is the downtime?

There is no downtime with PicoSure Focus facials. Patients may experience erythema that typically resolves within a few hours, but in some cases, may linger up to 24 hours. Since each patient is unique, we highly recommend following the outlined clinical guidelines to help optimise safety and efficacy before treatment.

How many treatments will it take to give my patients optimal results?

Most unwanted pigment will significantly lighten or clear in 2-3 sessions.

What side effects can occur?

Typically less than 5% of subjects observe side effects however they can occur and include:

  • Scarring, keloid formation and indentation of the tissue
  • Postoperative erythema, edema, and pain
  • Hypopigmentation or hyperpigmentation
  • Infection

The same complications and risks that exist for conventional or traditional surgery also exist for laser surgery. These include, but are not limited to the following:

  • Allergic reaction to medication
  • Arrhythmia
  • Pain
  • Ulceration
  • Fever
  • Delayed healing

Realself Rating as of May 2021.

©2022 Cynosure, LLC. All rights reserved. Cynosure, LLC owns exclusive rights to photography. Use of photography without written permission of Cynosure is prohibited. Cynosure, PicoSure and the Platinum Focus lens are registered trademarks and trademarks of Cynosure, LLC.

These before and after photographs are of a patient treated with Cynosure’s PicoSure device, not the PicoSure Pro device advertised herein. The PicoSure Pro device has the same parameters as the PicoSure device and so while individual results vary, similar results are expected.

Treatment of Tattoos with a Picosecond Alexandrite Laser: A Prospective Trial
Saedi N, Metelitsa A, Petrell K, et al. Arch Dermatol. 2012;148(12):1360-1363.

Use of a Picosecond Pulse Duration Laser with Specialized Optic for Treatment of Facial Acne Scarring
Brauer JA, Kazlouskaya V, Alabdulrazzaq H, et al. JAMA Dermatol. Published online November 19, 2014.

Picosecond Lasers: The Next Generation of Short-pulsed Lasers
Freedman J., Kaufman J., Metelitsa A., Seminars in Cutaneous Medicine and Surgery. Vol. 33, December 2014.

Treatment of Nevus of Ota with a Picosecond 755-nm Alexandrite Laser
Chesnut C., Diehl J., Lask G. Dermatol Surg. 2015;41:508–536.

Clearance of Yellow Tattoo Ink With a Novel 532-nm Picosecond Laser
Alabdulrazzaq H., Brauer J., Bae YS., Geronemus R. Lasers in Surgery and Medicine. 2015; Lasers in Surgery and Medicine 47:285–288.

Successful and Rapid Treatment of Blue and Green Tattoo Pigment with a Novel Picosecond Laser
Brauer JA, Reddy KK, Anolik R, et al. Arch Dermatol. 2012;148(7):820-823.

Your Practice & Cynosure

Keep your practice on top with the latest best-in-class offerings along with dedicated support and turnkey solutions when you partner with Cynosure.

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